Cancer Treatment Fertility Risks Mitigated by Pioneering Ovarian Preservation Research

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Scientists from the University of Saskatchewan are working to develop a pioneering research program with the potential to significantly improve the fertility prospects of women who have undergone cancer treatment. The primary thrust of the program is utilizing cryobiology to preserve healthy ovarian tissue in women and girls prior to their receiving any form of cancer treatment.

Cancer treatments can wreak havoc on the ovaries and pose a significant risk to fertility. However, by successfully freezing and preserving ovarian tissue, it can be re-implanted later, once the threat of cancer has been fully eradicated. This re-implantation could potentially pave the way for biological childbirth.


The research has progressed remarkably well, stepping from an early-phase concept to public use application. Already, similar research and clinical programs are in operation across Europe and the United States, marking a landmark moment for those affected.

Adult women have the option to preserve egg cells before cancer treatment, but the same is not true for girls who do not yet have mature egg cells. According to Dr. Laura Hopkins, an expert in gynecologic oncology, pediatric ovarian tissue is especially susceptible to damage from cancer treatments.

This innovative service restores options previously snatched away by the cruel hand of cancer. As Hopkins states, cancer treatment can lead to feelings of isolation and despair for anyone, let alone the loss of fertility and the potential halt in normal hormone production, which are pivotal to maintaining good health. Thankfully, given today’s advancements in treatment, most children are now surviving cancer. This program aims to give them a chance at reclaiming a semblance of normalcy in their lives.

The University of Saskatchewan possesses the much-needed expertise and state-of-the-art facilities to spearhead this groundbreaking program. The university is replete with researchers experienced in cryobiology, notably from the Western College of Veterinary Medicine.

Krysta Hawryluk, a patient of Hopkins who was diagnosed with ovarian cancer in 2020, posits that cryopreservation could provide women with the choice to have their own children post-cancer treatment. After her diagnosis, Hawryluk underwent an operation to have her ovaries removed.

She passionately advocates for this treatment, arguing that the decision to have biological children should not be bound by the snares of fate but should be a personal choice. The pioneering research at the University of Saskatchewan brings hope to women like Hawryluk, offering a silver lining when they need it most.